How many calories is one sugary drink? There are approximately 150 calories in one sugary drink; this is the same amount of calories found in two slices of bread. You can cut your calories easily by switching to water or unsweetened drinks. So, the next time you reach for a soda, energy drink, or sports drink, think about all of the calories, which primarily come from sugar. Sugar has 4 calories per gram and contains no nutritional value. In other words, the calories that come from sugar are “empty” calories. When monitoring the calories you eat each day, try to pack your calories with good nutrition to help protect against disease. Good nutrition calories come from natural food sources like fruits, vegetables and monounsaturated fats (avocados, nuts, olives, olive oil, etc.)